Study Examines Toxicity of PFAS Mixtures
October, 2024
A groundbreaking study has measured the toxicity of several types of PFAS (per- and polyfluoroalkyl substances), known as “forever chemicals,” when combined in the environment and human body. While individual PFAS chemicals showed relatively low toxicity, the study found that when mixed together, the entire combination became toxic. The research, led by Karla Ríos-Bonilla from the University at Buffalo and published in Environmental Science and Technology, focused on the effects of PFAS on cell lines testing for mitochondrial damage and neurotoxicity. It revealed that common PFAS like PFOA and PFOS significantly contribute to the overall toxicity of these mixtures.
This study is particularly important because it assesses PFAS toxicity in mixtures rather than individual chemicals, highlighting the need for new regulatory approaches. PFAS are widespread in consumer products and the environment, often contaminating water supplies and human blood. Though the U.S. Environmental Protection Agency (EPA) has set drinking water standards for six types of PFAS, over 15,000 varieties remain unregulated. The researchers stress that PFAS should be regulated as mixtures due to their combined harmful effects, and that toxicity testing can help assess the effectiveness of remediation efforts for polluted sites.
For further reading, please click here.

The PFAS Treatment Europe 2025 conference is a major industry event focused on advanced solutions for treating PFAS contamination. It brings together utilities, water companies, regulators, and industry experts to share the latest developments, strategies, and innovations for managing PFAS in Europe. Key topics include regulatory updates, remediation technologies, socio-economic impacts, and case studies from across the continent. Our CEO, Vincent Caillaud , will be in attendance.

WEFTEC 2025 is the world’s largest annual water quality conference and exhibition, held September 27–October 1, 2025, at McCormick Place in Chicago. It gathers over 20,000 water professionals from 100+ countries to explore cutting-edge water technologies, attend technical sessions and workshops, and network with sector leaders. The event features a massive exhibition of advanced solutions, educational opportunities, and speciality pavilions focused on topics like sustainability and digital innovation. Our CEO Vincent Caillaud , and CCO, Neal Megonnell , will be in attendance.

Neal Megonnell brings over three decades of experience in various leadership, technology and sales roles in the carbon industry to his new position at Puraffinity. His extensive background and expertise in the water treatment sector and the specific technologies for removing contaminants make him an invaluable addition to the company's executive team. In his role as CCO, Neal will be responsible for driving Puraffinity's commercial strategy, expanding market presence, and accelerating growth in the rapidly evolving field of PFAS removal technologies. "We are thrilled to welcome Neal to our team," said Vincent Caillaud, CEO of Puraffinity. "His impressive track record in the industry, coupled with his deep understanding of PFAS-related challenges, aligns perfectly with our mission. His background in R&D, with multiple published papers and two patents related to activated carbon, will be instrumental in driving our commercial success and furthering our goal of providing innovative PFAS removal solutions." Neal holds a Bachelor of Science degree in Chemistry from the University of Pittsburgh Master of Science degree in Chemical Engineering from Carnegie Mellon University and a Master’s in Colloids, Polymers and Surfaces. This strong academic foundation, combined with his extensive industry experience, positions him well to lead Puraffinity's commercial efforts in addressing one of the most pressing environmental challenges of our time. Neal's expertise is extensively demonstrated through his strategic involvement in various professional committees, including Chair of the American Water Works Association Standards on Activated Carbon Committee, the ASTM D28 Activated Carbon Committee, and serving as Chairman of the Standards for Activated Carbon. "I am thrilled to join Puraffinity at this exciting time," said Neal Megonnell. "The company's commitment to developing sustainable adsorbent materials for PFAS removal aligns with my passion for innovative water treatment solutions. I look forward to working with the talented team at Puraffinity to expand our market reach and deliver cutting-edge technologies to communities and industries worldwide."